The Vulnerable Atherosclerotic Plaque: Strategies for by Renu Virmani, Jagat Narula, Martin B. Leon, James T.

By Renu Virmani, Jagat Narula, Martin B. Leon, James T. Willerson

Eventually, a handy, one-volume precis of present wisdom on a space of accelerating value! The susceptible Atherosclerotic Plaque provides contributions from the simplest investigators within the box, skillfully edited for simple studying and lavishly illustrated with high quality, full-color photos.

After a thought of and concise advent, the e-book concentrates on:

  • Pathology of weak plaque
  • Triggers for plaque rupture
  • Imaging of volatile plaque
  • Management of susceptible plaques

Careful modifying permits the authors to prevent repetition and supply finished insurance of pathology, detection, and administration. This thorough and authoritative reference will switch the best way interventionists examine the disease.

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Additional info for The Vulnerable Atherosclerotic Plaque: Strategies for Diagnosis and Management

Example text

17 Mean number of thin-cap fibroatheromas and serum cholesterol in men. The bar plot is based on total population and race. The mean numbers of thin-cap fibroatheromas (TCFAs) are plotted against total cholesterol (TC) or total cholesterol/high-density lipoprotein cholesterol ratio (TC/HDL-C). The number of TCFAs are greatest in individuals with TC >210 and ratio >5. Whites generally demonstrated an increased incidence of TCFAs over blacks. 18 Mean number of thin-cap fibroatheromas in 51 women with sudden coronary death (SCD) and severe coronary disease.

03) than nonocclusive thrombi. 04) within the thrombus. 7% vs. 4%), this was not apparent for macrophages (13% vs. 20%). 16 Serial sections of a thin-cap fibroatheroma. Photomicrographs to show a vulnerable plaque with sections taken at every 200-mm interval in the coronary artery of a patient dying suddenly with acute thrombus with underlying plaque rupture. Note the gradual increase in the necrotic core size (arrowhead) from A to E and thereafter the necrotic core is large with a thin fibrous cap that is infiltrated with macrophages.

Few angiographic studies have demonstrated plaque progression and shortterm studies have suggested that thrombosis is the likely cause. 5 Morphometric analysis of thin-cap fibroatheromas. A, The percentage cross-sectional area luminal narrowing by type of plaque. The thin-cap fibroatheromas and fibroatheromas are less narrowed than plaque rupture and healed plaque rupture. B, Over 80% of thin-cap atheromas have <75% cross-sectional area luminal narrowing. 5A). TCFAs and fibroatheromas have the least luminal narrowing while lesions with acute plaque rupture, hemorrhage, or healed repair sites show the most stenosis.

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