Diagnosis and Treatment of Gastroesophageal Reflux Disease by Michael F. Vaezi

By Michael F. Vaezi

This quantity provides the newest advancements in analysis and therapy of sufferers with gastroesophageal reflux sickness (GERD) and those that remain refractory to standard GERD cures. The booklet delineates the position of newly built endoscopic treatments in GERD and descriptions the easiest applicants for surgical fundoplication. issues because the hazards linked to GERD, way of life amendment in GERD and the function of H2RA and proton pump inhibitor treatment in treating reflux ailment also are explored.

Written by means of specialists within the box, Diagnosis and remedy of Gastroesophageal Reflux illness is a concise but accomplished source that's worthwhile for basic care companies, gastroenterologists, pulmonologists, surgeons and ENT specialists.

Show description

Read or Download Diagnosis and Treatment of Gastroesophageal Reflux Disease PDF

Best pulmonary & thoracic medicine books

Endothelium : molecular aspects of metabolic disorders

The functionality and lifestyles span of endothelial cells have a wide impression upon the standard and expectancy of an individual's existence. in the course of low perfusion, the variation of other cells to hypoxia precipitate the competitive development of ailments. even supposing the medical reports have convincingly proven that endothelial disorder happens every time the organic capabilities or bioavailability of nitric oxide are impaired, in most of these situations, the function of endothelial cell-destructive approach cross-talk is but poorly understood.

Endothelial Cytoskeleton

This booklet provides a concise synthesis of the present wisdom and up to date advances within the constitution, association and sensible function of the cytoskeleton in endothelial cells. specific recognition has been given to the various positive aspects of the rules of vascular functionality mediated through the endothelium.

Pleural Diseases

Now in an absolutely revised and up to date 6th variation, Dr. Light's vintage textual content, Pleural illnesses, grants much more centred content material at the pathophysiology, medical manifestations, analysis, and administration of pleural illnesses. The text’s trouble-free, single-author point of view combines procedural services, insights on contemporary technical advances, and transparent strategies for either analysis and therapy.

Nutritional Management of Inflammatory Bowel Diseases: A Comprehensive Guide

This ebook is a state-of-the paintings evaluation for clinicians and dieticians with an curiosity in nutrients and inflammatory bowel ailments (Crohn’s sickness, ulcerative colitis). the amount covers new facts approximately nutritional probability components for Crohn’s disorder and ulcerative colitis, examines the organization among vitamin and microbiome, describes a few of the diets within the administration of those ailments, and discusses macro- and micronutrient deficiency that happens in such sufferers.

Extra resources for Diagnosis and Treatment of Gastroesophageal Reflux Disease

Sample text

Therefore, advanced imaging techniques may provide endoscopy with an improved sensitivity for the diagnosis of GERD. Esophageal Biopsy The addition of esophageal biopsies to endoscopy allows for histologic assessment in order to assess for microscopic mucosal injury, rule out alternative diagnoses such as eosinophlic esophagitis, and assess for disease complications such as the development of Barrett’s esophagus or neoplasia. Early histologic studies in asymptomatic patients and in whom no reflux was demonstrated by pH studies detailed the normal histologic appearance of the esophageal mucosa characterized by dermal papillae that extended less than halfway to the free luminal margin and a basal cell 3 Diagnostic Approaches to GERD 43 layer occupying less than 15 % of the total thickness of the epithelium.

The primary indications for ambulatory 24-h esophageal pH monitoring are (1) to document excessive acid reflux in patients with suspected GERD but without endoscopic esophagitis, (2) to assess reflux frequency, and (3) to assess symptom association. Standard ambulatory 24-h esophageal pH monitoring measures distal esophageal acid exposure by using a single pH electrode catheter that is passed through the nose and positioned 5 cm above the superior margin of the manometrically determined LES. Although other techniques for electrode placement exist, such as pH step-up (rise in pH from stomach to esophagus) and endoscopic and fluoroscopic placement, they are less accurate and not standardized [38, 39].

Whether such practice can be supported from a resource utilization standpoint may be sensitive to refined estimates of malignant progression, as well as the need for posttreatment endoscopic surveillance. Conclusion Patients with chronic GERD are at risk for development of esophageal pathology. While the prevalence of peptic esophageal stricture has become less common in the era of potent pharmacologic antisecretory therapy, attention is now instead focused upon premalignant and malignant esophageal pathology in the context of an increasing prevalence of EAC.

Download PDF sample

Rated 4.09 of 5 – based on 24 votes