By Joachim W. Fluhr, Peter Elsner, Enzo Berardesca, Howard I. Maibach
Bioengineering of the surface, or extra exactly the biophysical review of pores and skin body structure, is relocating quickly from a descriptive method of a deeper realizing of biophysical and biochemical procedures. This moment variation of the preferred textual content Bioengineering of the outside: Water and Stratum Corneum displays the development within the box, targeting the dramatically greater knowing of dermis body structure. particularly, it studies the shift in our realizing of the stratum corneum from an inert surrounding sheet to a biologically lively compartment.
The stratum corneum is the interface among the occasionally harsh setting and the inner turmoil of the human physique. in accordance with various contemporary courses, this ebook explains the mechanisms serious about stratum corneum barrier functionality and hydration. It displays 10 years of development not just of the non-invasive biophysical overview of epidermis body structure parameter, but additionally of the perfection of the on hand units. It brings all study on epidermal water and transepidermal water loss in future health and sickness up to date with the revision of present chapters in addition to additional chapters from new individuals on hydration and itching. This variation additionally comprises new guidance at the standardization of measurements.
Bioengineering of the outside will improve communique in the study group and should be helpful for scientists within the epidermis bioengineering box by means of featuring equipment that provide trustworthy and reproducible techniques for product trying out within the pharmaceutical and beauty industries, in addition to for uncomplicated learn
Read Online or Download Bioengineering of the Skin: Water and the Stratum Corneum, 2nd Edition PDF
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Bioengineering of the surface, or extra exactly the biophysical overview of dermis body structure, is relocating speedily from a descriptive method of a deeper figuring out of biophysical and biochemical methods. This moment version of the preferred textual content Bioengineering of the outside: Water and Stratum Corneum displays the growth within the box, concentrating on the dramatically superior figuring out of epidermis body structure.
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Additional info for Bioengineering of the Skin: Water and the Stratum Corneum, 2nd Edition
Skin barrier structure and function: the single gel phase model, J. Invest. , 117, 830, 2001. 65. , Does the single gel phase exist in stratum corneum? J. Invest. , 118, 897, 2002. 66. Ge, M. et al. Electron spin resonance characterization of liquid ordered phase of detergent-resistant membranes from RBL-2H3 cells, Biophys. , 77, 925, 1999. 67. M. , Epidermal lipid liposomes: a novel non-phospholipid membrane system, Biochem. Soc. , 7, 1129, 1979. 68. W. et al. Preparation of liposomes from stratum corneum lipids, J.
Similarly, little is known on the role of intercellular lipids, except for their barrier function. The information presented in this chapter was derived from data obtained in vitro. The situation in vivo is of course highly different; for example, there is a hydration gradient between the external layer and the internal layers. This gradient is responsible for the continuous flow of water vapor across the SC. In addition, sweat secretion — both continuous and discontinuous — plays an important role in the hydration of the SC.
Suggested a correlation between SC lipid fluidity and water content . These studies clearly demonstrate that there is an interaction between lipids and water , but a comprehensive model of this interaction still does not exist. 1 shows the very large difference in the cystine content of the constituent proteins. , Keratins. C. Thomas, New York, 1972. maximum water uptake. 2, which shows the absorption isotherms for water of the SC and hair. In the zone of moderate humidity, the pattern is similar for the two tissues, probably because the nature of the substrate controls the phenomenon, as we shall see later.