Tumor Prevention and Genetics III (Recent Results in Cancer by H.-J. Senn, R. Morant

By H.-J. Senn, R. Morant

This quantity includes the vast majority of the invited keynote lectures provided by means of specialists on the 3rd foreign convention on Controversies in Tumor Prevention and Genetics on 12-14 February 2004 in St.Gallen, Switzerland. jointly, they show the most recent findings in oncogenetics and its family members to fresh and destiny advancements in fundamental and secondary tumor prevention, particularly in breast, colon and lung melanoma. All contributions are written and feature been significantly reviewed by way of the world over acknowledged leaders within the box.

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41 6 Conclusion . . . . . . . . . . . . . . . . . . . 42 References . . . . . . . . . . . . . . . . . . . . . 43 Abstract Gastric cancer has been declining for more than half a century, whereas the incidence of oesophageal cancer is increasing rapidly. The histopathological subtype is also changing with a predominance of oesophageal adenocarcinoma compared with squamous carcinoma. The reasons for these epidemiological changes are not clear, although population-based data have implicated gastro-oesophageal reflux disease as a risk factor.

33]) relation between the change in BMI and the reduction in SHBG in our studies, supporting our contention that obesity is not the real cause of many of the abnormalities observed in obese individuals. We also recently showed that the diet-and-exercise program does reduce serum-free testosterone [54].

57 References . . . . . . . . . . . . . . . . . . . . . 58 Abstract Metabolic syndrome was initially described as an aggregation of risk factors for the development of coronary artery disease with insulin resistance and compensatory hyperinsulinemia as the underlying factor. In an earlier review, we suggested that hyperinsulinemia may also lead to prostate cancer (PCa), the most common male cancer in industrialized nations. Furthermore, we suggested that diet and exercise, known to be important in the development of insulin resistance, may also be important in the development of PCa.

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