Quantitative Functional Brain Imaging with Positron Emission by Richard E. Carson, Peter Herscovitch, Margaret E.

By Richard E. Carson, Peter Herscovitch, Margaret E. Daube-Witherspoon

This booklet provides the newest medical advancements within the box of positron emission tomography (PET) facing information acquisition, photograph processing, purposes, statistical research, tracer improvement, parameter estimation, and kinetic modeling. It covers stronger technique and the appliance of current concepts to new components. The textual content additionally describes new ways in scanner layout and snapshot processing, and the newest thoughts for modeling and statistical analyses. This quantity may be an invaluable reference for the lively mind puppy scientist, in addition to a priceless advent for college kids and researchers who desire to reap the benefits of the services of puppy to review the traditional and diseased mind. Key good points* Authored by means of foreign professionals in puppy* offers the newest up to date strategies and purposes* Covers all primary disciplines of puppy in a single quantity* A entire source for college students, clinicians, and new puppy researchers

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Simultaneous PET / MR Images of the Brain TABLE 2 PET Data Acquisition and I m a g e Reconstruction Parameters Phantom source activity - ImCi Coincidence count rate ^ 1 1 5 per second (at beginning) Total events collected - 58,000 Slice thickness 1 mm (FWHM) Reconstruction method Filtered backprojection Reconstruction filter Ramp (Nyquist frequency) tion, a circular plastic tube filled with NiS04 solution was aligned with the PET imaging plane and attached to the outside of the PET detector ring holder.

Data are reconstructed using filtered backprojection with the depth of interaction information incorporated by the rebinning algorithm described later. The results of this simulation are shown in Fig. 1, which plots the FWHM of the reconstructed line source image (in the radial direction) as a function of distance from the tomograph center. Tomographs with several different DOI measurement resolutions are simulated. Without DOI information, the familiar radial elongation artifact degrades the spatial resolution by a factor of 3 at a distance of 10 cm from the tomograph center.

C. Image Artifact and Distortion Studies Experiments were conducted to investigate image artifacts and distortions in both PET and MR images that may possibly result from simultaneous data acquisition. To assess possible MR image degradation due to the presence of the PET detector system, a 2-cm-diameter, 5-mm axial extent cylindrical phantom was used. This uniform phantom was chosen in order to have a relatively large object volume for examining any possible artifact or distortion inside the imaging volume.

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