Philosophy of Systems Biology: Perspectives from Scientists by Sara Green

By Sara Green

The emergence of platforms biology increases many desirable questions: What does it suggest to take a structures method of difficulties in biology? To what volume is using mathematical and computational modelling altering the lifestyles sciences? How does the supply of huge info impression study practices? What are the main demanding situations for biomedical study within the future years? This ebook addresses such questions of relevance not just to philosophers and biologists but additionally to readers drawn to the wider implications of platforms biology for technology and society.

The e-book beneficial properties reflections and unique paintings through specialists from around the disciplines together with structures biologists, philosophers, and interdisciplinary students investigating the social and academic elements of structures biology. in keeping with an analogous set of questions, the specialists improve and safeguard their own views at the particular personality of platforms biology and the demanding situations that lie forward. Readers are invited to interact with assorted perspectives at the questions addressed, and will discover a variety of issues when it comes to the philosophy of structures biology.

This edited paintings will entice students and all degrees, from undergraduates to researchers, and to these drawn to various scholarly ways reminiscent of platforms biology, mathematical and computational modelling, phone and molecular biology, genomics, platforms idea, and naturally, philosophy of biology.

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S. (2012). The roles of integration in molecular systems biology. Studies in History and Philosophy of Biological and Biomedical Sciences, 43, 58–68. , & Pall, C. (2011). Systems-biology approaches for predicting genomic evolution. Nature Review Genetics, 12, 591–602.  H. (2015). Genomic control process in development and evolution. London: Academic Press/Elsevier.  H. (2012). Feature article: Predictive computation of genomic logic processing functions in embryonic development. Proceedings of the National Academy of Sciences of the United States of America, 109, 16434–16442.

This may be easier for philosophers than for scientists since we do not have laboratories to run, and investigating the scientific results and processes is the object of our research. But we can also do more to make our work relevant to scientists by presenting our philosophical analyses in the context relevant to the scientists’ research. , a philosopher who takes as his mission to characterize science as it is actually done) in systems biology. Much of my work has focused on explanation and what systems biology provides are examples of different strategies for explaining phenomena than those I have examined previously.

5). 1 Introduction to Philosophy of Systems Biology 13 has been discussed in the context of stem cell research where prioritization of different standards of explanation has blocked collaboration and communication (Fagan 2016; Chap. 8). Modelers drawing on dynamical systems biology view in silico reproduction of dynamic behaviors of stem cells as a major breakthrough and picture their approach as superior to the mechanistic analysis conducted by ­experimentalists. Experimentalists have, however, largely ignored these contributions as they see these as merely restating what is already known about the system.

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